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Mozaffar.mahmoodi@uniq.edu.iq
Background: To determine the efficacy of treatment of central nervous system (CNS) hemangioblastomas in von Hippel-Lindau disease (VHL), long-term outcomes in patients with hemangioblastoma and VHL variant were accepted. Hemangioblastoma is rare, histological origin. Highly vascularized tumors that can be found throughout the neuraxis but are mainly located in the cerebellum and in the spinal cord. The most common primary tumor of the posterior fossa in adults. Hemangioblastomas may also occur within the spine. Material and Methods: This meta-analysis was performed to evaluate headaches in Hemangioblastoma (HBL) tumors structurally and separately based on randomized controlled trial studies. Electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) were searched for randomized and controlled trial studies that searched for the results of treatment of brain tumors (Hemangioblastoma type) and headache in Hemangioblastoma (HBL) tumors. Result: This meta-analysis was performed using Review Manager (Rev Man) software (version 5.2) provided by Cochrane Collaboration. The data used were hazard ratios with 95% confidence intervals calculated for time-to-event data extracted from survival curves and local tumor control rate curves. A consecutive series of patients with hemangioblastomas on between 2010 and 2020 by the senior author (A. AN) is Reviewed. Conclusion: Adequate knowledge of the treatment and correct use of microsurgical techniques allows complete resection of these tumors with minimal complications and maximum functional improvement. The result appears to be directly related to the preoperative condition.
