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Mozaffar.mahmoodi@uniq.edu.iq
Hemangioblastoma (HBL) are rare, benign, s highly vascularized tumor of not well-defined histological origin. highly vascularized tumors that can be found throughout the neuraxis but are mainly located in the cerebellum and in the spinal cord. the most common primary tumor of the posterior fossa in adults. Hemangioblastomas may also occur within the spine. Single tumors may be sporadic, but multiple tumors are almost always associated with von Hippel-Lindau (VHL) disease. Sporadic tumors appear in the fifth and sixth decades of life, whereas VHL-associated tumors are detected earlier, in the third and fourth decades. One-third of patients with cerebellar hemangioblastoma have VHL disease. Two-thirds of VHL patients develop hemangioblastomas; thus screening and surveillance programs are required for this population. This meta-analysis was performed to evaluate headache in Hemangioblastoma (HBL) tumors structurally and separately based on randomized controlled trial studies. Electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) were searched for randomized and controlled trial studies that searched for the results of treatment of brain tumors (Hemangioblastoma type) and headache in Hemangioblastoma (HBL) tumors. This meta-analysis was performed using Review Manager (RevMan) software (version 5.2) provided by Cochrane Collaboration. The data used were hazard ratios with 95% confidence intervals calculated for time-to-event data extracted from survival curves and local tumor control rate curves. A consecutive series of patients with hemangioblastomas on between 1985 and 2010 by the senior author (A.AN) is Reviewed. The functional scale proposed by McCormick was used to evaluate the patients’ neurological status before and after surgery. Adequate knowledge for the treatment and correct use of microsurgical techniques allows complete resection of these tumors with minimal complications and maximum functional improvement. The result appears to be directly related to the preoperative condition.
